"With the help of more than five dozen fossils, paleontologists have uncovered a tiny three-eyed predator nicknamed the 'sea moth'," reports CNN, "that swam in Earth's oceans 506 million years ago." Tiny as in 15 to 61 mm in total body length. (That's 0.60 to 2.4 inches...) But check out the illustration in CNN's article... Mosura fentoni, as the species is known, belongs to a group called radiodonts, an early offshoot of the arthropod evolutionary tree, according to a new study published Tuesday in the journal Royal Society Open Science. While radiodonts are now extinct, studying their fossilized remains can illuminate how modern arthropods such as insects, spiders and crabs evolved. One of the most diverse animal groups, arthropods are believed to account for more than 80% of living animal species, said lead study author Dr. Joe Moysiuk, curator of paleontology and geology at the Manitoba Museum in Winnipeg. Well-preserved specimens of the previously unknown Mosura fentoni also reveal something that's never been seen in any other radiodont: an abdomen-like body region with 16 segments that include gills at its rear. This part of the creature's anatomy is similar to a batch of segments bearing respiratory organs at the rear of the body found in distant modern radiodont relatives like horseshoe crabs, woodlice and insects, Moysiuk said.... No animal living today quite looks like Mosura fentoni, Moysiuk said, although it had jointed claws similar to those of modern insects and crustaceans. But unlike those critters, which can have two or four additional eyes used to help maintain orientation, Mosura had a larger and more conspicuous third eye in the middle of its head. "Although not closely related, Mosura probably swam in a similar way to a ray, undulating its multiple sets of swimming flaps up and down, like flying underwater," Moysiuk said in an email. "It also had a mouth shaped like a pencil sharpener and lined with rows of serrated plates, unlike any living animal." About the size of an adult human's index finger, Mosura and its swimming flaps vaguely resemble a moth, which led researchers to call it the "sea moth." The Royal Society publication notes the etymology of the species name (Mosura fentoni is "from the name of the fictional Japanese monster, or kaiju... also known as 'Mothra'...in reference to the moth-like appearance of the animal." Thanks to long-time Slashdot reader walterbyrd for sharing the news.

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Scientists have successfully treated a 9.5-month-old boy with an ultra-rare genetic disorder using the world's first personalized gene-editing therapy. The patient, identified as KJ, has CPS1 deficiency -- a condition affecting just one in 1.3 million babies that prevents proper ammonia processing and is often fatal. The breakthrough treatment, detailed in the New England Journal of Medicine, uses base editing technology to correct KJ's specific DNA mutation. The therapy delivers CRISPR components wrapped in fatty lipid molecules that protect them in the bloodstream until they reach liver cells, where they make the precise edit needed. After three infusions, KJ now eats normal amounts of protein and has maintained stable ammonia levels even through viral illnesses that would typically cause dangerous spikes. His weight has increased from the 7th to 40th percentile. Dr. Peter Marks, former FDA official, called the approach "one of the most potentially transformational technologies" because it could be rapidly adapted for thousands of other rare genetic diseases without lengthy development cycles.

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Longtime Slashdot reader ndsurvivor shares a report from TechCrunch: In 2018, Liangbing Hu, a materials scientist at the University of Maryland, devised a way to turn ordinary wood into a material stronger than steel. It seemed like yet another headline-grabbing discovery that wouldn't make it out of the lab. "All these people came to him," said Alex Lau, CEO of InventWood, "He's like, OK, this is amazing, but I'm a university professor. I don't know quite what to do about it." Rather than give up, Hu spent the next few years refining the technology, reducing the time it took to make the material from more than a week to a few hours. Soon, it was ready to commercialize, and he licensed the technology to InventWood. Now, the startup's first batches of Superwood will be produced starting this summer. "Right now, coming out of this first-of-a-kind commercial plant -- so it's a smaller plant -- we're focused on skin applications," Lau said. "Eventually we want to get to the bones of the building. Ninety percent of the carbon impact from buildings is concrete and steel in the construction of the building." To build the factory, InventWood has raised $15 million in the first close of a Series A round. The round was led by the Grantham Foundation with participation from Baruch Future Ventures, Builders Vision, and Muus Climate Partners, the company exclusively told TechCrunch. How do they do it? According to TechCrunch, InventWood's Superwood is made by treating regular timber with "food industry" chemicals to remove lignin and modify its structure, then compressing it to increase hydrogen bonding between cellulose fibers. This densification makes the wood up to 10 times stronger than natural wood, with a higher strength-to-weight ratio than steel. "You end up with something that looks like these richer, tropical hardwoods," Lau added.

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sciencehabit shares a repot from Science.org: Scientists have captured fungal spores cruising in the inhospitable environment of the stratosphere, much higher than commercial aircraft fly. When brought back to the lab, the researchers found that some of the spores -- including pathogens of plants and people -- had survived intercontinental trips and could be cultured in the lab. Although spores and microbes have been detected in the stratosphere before, the new results come from a cheap, homespun sampling device dangled from weather balloons, the project could help researchers figure out what traits and conditions allow spores to survive a swing through the stratosphere and how they get up there in the first place. The work could also be a first step towards an atmospheric monitoring system that could nip emerging fungal pathogens in the bud, the study's authors reported at a conference of the European Geophysical Union. After five preliminary flights, the team has already learned a lot. Based on DNA sequencing analysis, they identified spores from 235 genera, including fungi that infect blackberries and carrots in the United States and Japan, and one species, Naganishia albida, that can make immunocompromised people sick. In the lab, they were able to revive and culture spores from 15 different fungal species, among them several plant pathogens. Mostly, the results show that their sampler works. Now, the researchers want to set up regular flights to track airborne fungal biodiversity and seasonal variations. They also want to identify how events such as wildfires or volcanic eruptions inject spores into the stratosphere.

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Researchers have discovered a mutation in the SIK3 gene that enables some people to function normally on just three to six hours of sleep. The finding, published this week in PNAS, adds to a growing list of genetic variants linked to naturally short sleepers. When University of California, San Francisco scientists introduced the mutation to mice, the animals required 31 minutes less sleep daily. The modified enzyme showed highest activity in brain synapses, suggesting it might support brain homeostasis -- the resetting process thought to occur during sleep. "These people, all these functions our bodies are doing while we are sleeping, they can just perform at a higher level than we can," said Ying-Hui Fu, the study's co-author. This marks the fifth mutation across four genes identified in naturally short sleepers. Fu's team hopes these discoveries could eventually lead to treatments for sleep disorders by revealing how sleep regulation functions in humans.

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"Researchers have created the first laboratory analog of the 'black hole bomb'," reports ScienceAlert, "a theoretical concept developed by physicists in the 1970s..." There's no black hole involved; their experiment just simulates the "electromagnetic analogue" of the theoretical concept — the "exponential runaway amplification of spontaneously generated electromagnetic modes." Or, as ScienceAlert puts it, "It doesn't, just to set your mind at ease, pose any danger. It consists of a rotating aluminum cylinder, placed inside layers of coils that generate magnetic fields that rotate around it, at controllable speeds." As Roger Penrose proposed in 1971, the powerful rotational energy of a spinning black hole could be used to amplify the energy of nearby particles. Then, physicist Yakov Zel'Dovich figured out that you didn't need a black hole to see this phenomenon in action. An axially symmetrical body rotating in a resonance chamber, he figured, could produce the same energy transfer and amplification, albeit on a much smaller scale. Later work by other physicists found that, if you enclose the entire apparatus in a mirror, a positive feedback loop is generated, amplifying the energy until it explodes from the system. This concept was named the black hole bomb, and a team of physicists led by Marion Cromb of the University of Southampton in the UK now claim to have brought it to life. A paper describing their experiment has been uploaded to preprint server arXiv... [W]hat the team's experiment does is simulate it, using magnetic fields as a proxy for the particles, with the coils around the system acting as the reflector to produce the feedback loop. When they ran the experiment, they found that, when the cylinder is rotating faster than, and in the same direction as, the magnetic field, the magnetic field is amplified, compared to when there is no cylinder. When the cylinder rotates more slowly than the magnetic field, however, the magnetic field is dampened. This is a really interesting result, because it demonstrates a very clear amplification effect, based on the theories described decades ago... Because we can't probe black holes directly, analogs such as this are an excellent way to understand their properties... [T]he experiment could represent a significant step towards better understanding the physics of the most gravitationally extreme objects in the Universe. "The exponential amplification from noise supports theoretical investigations into black hole instabilities," the researchers write, "and is promising for the development of future experiments to observe quantum friction in the form of the Zeldovich effect seeded by the quantum vacuum..."

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A thought experiment involving a cat trapped in a steel box with a potentially lethal device, first proposed by physicist Erwin Schrodinger in 1935, remains at the center of scientific and philosophical debate as it marks its 90th anniversary. The paradox, initially published in a technical review of quantum mechanics, presented a scenario where a cat could theoretically exist in a superposition of states -- both alive and dead simultaneously -- until observed, highlighting profound questions about quantum reality. "Schrodinger understood that under no circumstances could his cat be considered to be both alive and dead at the same time," science writer Jim Baggott noted in a recently published essay. Baggott co-authored "Quantum Drama: From the Bohr-Einstein Debate to the Riddle of Entanglement" in 2024. The thought experiment gained cultural traction largely through science fiction writer Ursula Le Guin's 1974 short story "Schrodinger's Cat," which wrestled with the paradox's philosophical implications. This sparked widespread appearances across literature, film, and television. The paradox continues to divide physicists between those accepting quantum mechanics as a mathematical framework for prediction and others, like Einstein and Schrodinger himself, who considered the theory fundamentally incomplete.

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An anonymous reader writes: NIH Director Dr. Jay Bhattacharya has announced that the NIH Public Access Policy, originally slated to go into effect on December 31, 2025, will now be effective as of July 1. From Bhattacharya's announcement: NIH is the crown jewel of the American biomedical research system. However, a recent Pew Research Center study shows that only about 25% of Americans have a "great deal of confidence" that scientists are working for the public good. Earlier implementation of the Public Access Policy will help increase public confidence in the research we fund while also ensuring that the investments made by taxpayers produce replicable, reproducible, and generalizable results that benefit all Americans. Providing speedy public access to NIH-funded results is just one of the ways we are working to earn back the trust of the American people. Trust in science is an essential element in Making America Healthy Again. As such, NIH and its research partners will continue to promote maximum transparency in all that we do.

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NIST: Clocks on Earth are ticking a bit more regularly thanks to NIST-F4, a new atomic clock at the National Institute of Standards and Technology (NIST) campus in Boulder, Colorado. This month, NIST researchers published a journal article establishing NIST-F4 as one of the world's most accurate timekeepers. NIST has also submitted the clock for acceptance as a primary frequency standard by the International Bureau of Weights and Measures (BIPM), the body that oversees the world's time. NIST-F4 measures an unchanging frequency in the heart of cesium atoms, the internationally agreed-upon basis for defining the second since 1967. The clock is based on a "fountain" design that represents the gold standard of accuracy in timekeeping. NIST-F4 ticks at such a steady rate that if it had started running 100 million years ago, when dinosaurs roamed, it would be off by less than a second today. By joining a small group of similarly elite time pieces run by just 10 countries around the world, NIST-F4 makes the foundation of global time more stable and secure. At the same time, it is helping to steer the clocks NIST uses to keep official U.S. time. Distributed via radio and the internet, official U.S. time is critical for telecommunications and transportation systems, financial trading platforms, data center operations and more.

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Major scholarly databases have removed dozens of academic journals after researchers discovered they had been purchased by questionable companies and transformed into predatory publications. A January 2025 study identified 36 legitimate journals acquired by recently formed firms with no publishing experience, who then dramatically increased publication fees and output while lowering quality standards. According to information scientist Alberto Martin-Martin from the University of Granada, publishers are being offered up to hundreds of thousands of euros per journal title. Once acquired, journals typically introduce or raise article-processing charges while churning out papers often outside the publication's original scope. Scopus has delisted all 36 identified journals, and Web of Science removed 11 of 17 affected titles from its index. "As there has been significant change (different ownership), there is no guarantee that review quality is at the same level as the original journals," an Elsevier spokesperson told Nature.

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C'est assez fou : exposer quelqu'un - ne serait-ce qu'une minute - à un son de 100 Hz suffirait à réduire les nausées dues au mal des transports.
(Via https://nicolas-delsaux.hd.free.fr/Shaarli/shaare/NtDtJw)
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Researchers at UC Berkeley claim to have induced a previously unseen color by using lasers to stimulate only the M cones in the retina, creating a visual experience beyond the natural limits of human perception. Called olo, the color is described as a highly saturated blue-green but is only visible through direct retinal manipulation. The Guardian reports: "We predicted from the beginning that it would look like an unprecedented color signal but we didn't know what the brain would do with it," said Ren Ng, an electrical engineer at the University of California, Berkeley. "It was jaw-dropping. It's incredibly saturated." The researchers shared an image of a turquoise square to give a sense of the color, which they named olo, but stressed that the hue could only be experienced through laser manipulation of the retina. "There is no way to convey that color in an article or on a monitor," said Austin Roorda, a vision scientist on the team. "The whole point is that this is not the color we see, it's just not. The color we see is a version of it, but it absolutely pales by comparison with the experience of olo." The findings have been published in the journal Science Advances.

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Bruce66423 shares a report: Toothpaste can be widely contaminated with lead and other dangerous heavy metals, new research shows. Most of 51 brands of toothpaste tested for lead contained the dangerous heavy metal, including those for children or those marketed as green. The testing, conducted by Lead Safe Mama, also found concerning levels of highly toxic arsenic, mercury and cadmium in many brands. About 90% of toothpastes contained lead, 65% contained arsenic, just under half contained mercury, and one-third had cadmium. Many brands contain a number of the toxins. The highest levels detected violated the state of Washington's limits, but not federal limits. The thresholds have been roundly criticized by public health advocates for not being protective -- no level of exposure to lead is safe, the federal government has found. Bruce66423 asks: "As ever the question that should be asked is: 'What level is worth worrying about and why?'"

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Nature has published an analysis of the 21st century's most-cited scientific papers, revealing a surprising pattern: breakthrough discoveries like mRNA vaccines, CRISPR, and gravitational waves don't make the list. Instead, a 2016 Microsoft paper on "deep residual learning" networks claims the top spot, with citations ranging from 103,756 to 254,074 depending on the database. The list overwhelmingly features methodology papers and software tools rather than groundbreaking discoveries. AI research dominates with four papers in the top ten, including Google's 2017 "Attention is all you need" paper that underpins modern language models. The second-most-cited paper -- a 2001 guide for analyzing gene expression data -- was explicitly created to be cited after journal reviewers rejected references to a technical manual. As sociologist Misha Teplitskiy noted, "Scientists say they value methods, theory and empirical discoveries, but in practice the methods get cited more."

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Sage has retracted 678 more papers from the Journal of Intelligent and Fuzzy Systems (JIFS), concluding an investigation that has now purged 1,561 articles -- the most ever removed from a single journal. The publisher, which acquired JIFS from IOS Press in November 2023, began investigating the journal in early 2024 after discovering "indicators that raised concerns about the authenticity of the research and the peer review process." This final batch follows 467 articles retracted in August and another 416 in January. Problems in the retracted papers included citation manipulation, "tortured phrases," unauthorized third-party involvement in submissions, and evidence suggesting collusion between authors and reviewers. Most authors were from India and China, with some from Pakistan, Turkey, Iran, and Iraq. Cengiz Kahraman of Istanbul Technical University, who authored 20 of the retracted papers, disputed the decision, telling Retraction Watch that Sage acted "without any reason and evidence." The journal has now resumed publishing.

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In a recent interview with Wired, Nobel laureate Venkatraman Ramakrishnan discusses his book Why We Die, in which he argues that death is not genetically programmed but rather a consequence of evolution favoring reproduction over longevity. Here are some of the most thought-provoking excerpts: WIRED: Professor Ramakrishnan, the crucial question in your book is why we die. But exactly what is death? Venki Ramakrishnan: By death, we mean the irreversible loss of the ability to function as a coherent individual. It is the result of the failure of a critical system or apparatus, for example, heart, brain, lung, or kidney failure. In this sense there is an apparent paradox: When our organism, as a whole, is alive, millions of cells within us are constantly dying, and we do not even realize it. On the other hand, at the time of death, most of the cells in our bodies are still alive, and entire organs are still functioning and can be donated to people in need of transplantation. But at that point the body has lost the ability to function as a whole. In this sense, it is therefore important to distinguish between cell death and death of the individual. Speaking of death and aging, you say in your most recent book that you "wanted to offer an objective look at our current understanding of the two phenomena." What was the biggest surprise or most deeply held belief that you had to reconsider while writing and researching this work? There have been several surprises, actually. One is that death, contrary to what one might think, is not programmed by our genes. Evolution does not care how long we live, but merely selects the ability to pass on our genes, a process known as "fitness" in evolutionary biology. Thus, the traits that are selected are those that help us survive childhood and reproduce. And it is these traits, later in life, that cause aging and decline. Another curious finding was the fact that aging is not simply due to wear and tear on cells. Wear and tear happens constantly in all living things, yet different species have very different lifespans. Instead, lifespan is the result of a balance between the expenditure of resources needed to keep the organism functioning and repairing it and those needed to make it grow, mature, and keep it healthy until it reproduces and nurtures offspring. Do you think there is an aspect of the biology of aging that is still deeply misunderstood by the general public? Certainly the indefinite extension of life. Although in principle there are no laws or constraints that prevent us from living much longer than we do currently, great longevity or "eternal youth" are still far off, and very significant obstacles to increasing our maximum life expectancy remain. We must also beware of the pseudoscience -- and business -- around the concepts of "anti-aging" or the "reversal of aging." These are often baseless concepts, unsupported by hard evidence, even though they may use language that sounds scientific. Unfortunately, we are all afraid of growing old and dying, so we are very sensitive to any claim that promises to help us avoid it. [...] What do you think are the social and ethical implications of our desire to live longer? Ever since we became aware of our mortality, we have desired to defeat aging and death. However, our individual desires may conflict with what is best for society. A society in which fertility rates are very low and lifespans are very high will be a stagnant society, with very slow generational turnover, and probably much less dynamic and creative. The Nobel Prize-winning South American novelist Mario Vargas Llosa, who recently passed away, expressed it best: "Old age on the one hand terrifies us, but when we feel anxious, it is important to remember how terrible it would be to live forever. If eternity were guaranteed, all the incentives and illusions of life would vanish. This thought can help us live old age in a better way."

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Researchers at the University of Tokyo have created what they believe is the largest single piece of lab-grown meat to date: a chicken nugget-sized chunk measuring 7 centimeters long, 4 centimeters wide, and 2.25 centimeters thick, weighing 11 grams. The breakthrough, reported today in Trends in Biotechnology, uses an artificial circulatory system to overcome a fundamental limitation in cultured meat production. The team, led by biohybrid system engineer Shoji Takeuchi, grew cells around a network of semipermeable hollow fibers -- similar to those used in water filters and dialysis machines -- that deliver nutrients and oxygen throughout the tissue. Unlike most commercial approaches that produce tiny meat fragments later assembled with binders or scaffolds, this method creates a single coherent piece with more natural structure and texture. This is the first working model using tubes to grow muscle tissue into a thick slab, according to Mark Post, chief science officer at Mosa Meat, who created the world's first lab-grown hamburger in 2013. Significant hurdles remain before commercialization. The hollow fibers aren't edible and must be manually removed. Researchers are exploring automating this process or creating edible alternatives using cellulose.

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For the first time -- and despite fears that it might never happen -- nations have agreed a series of measures to prevent, prepare for and respond to pandemics. Nature: The terms of the first global pandemic accord were still being hashed out at the World Health Organization (WHO) headquarters in Geneva, Switzerland, up until the early hours of 16 April. "This is a definitive moment in the history of global health," says Lawrence Gostin, a specialist in health law and policy at Georgetown University in Washington DC, who followed the negotiations closely. The accord "sets out some very important norms to keep the world safe," he says. The accord was agreed without the United States, which withdrew from the pandemic treaty the day that President Trump was inaugurated. This reduces its power, says Gostin, but is also a source of strength. "Instead of collapsing in the face of President Trump's assault on global health, the world came together." The treaty is not perfect but represents a major achievement, says Michelle Childs, policy advocacy director at the non-profit organization Drugs for Neglected Diseases Initiative in Geneva. "People didn't think that they'd get to this stage of agreeing at all."

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"Researchers say that a person's intelligence plays a bigger role in their computer proficiency than previously believed," writes SciTechDaily, "so much so that practice alone may not be enough to ensure ease of use." A new study has found that general cognitive abilities, such as perception, reasoning, and memory, are more important than previously believed in determining a person's ability to perform everyday tasks on a computer... "It is clear that differences between individuals cannot be eliminated simply by means of training," says Antti Oulasvirta [a professor at Finland's Aalto University who conducted extensive human-computer interaction research with his team and the University of Helsinki Department of Psychology]. "In the future, user interfaces need to be streamlined for simpler use. This age-old goal has been forgotten at some point, and awkwardly designed interfaces have become a driver for the digital divide. "We cannot promote a deeper and more equal use of computers in society unless we solve this basic problem," Oulasvirta says... This is the first-ever study to measure users' actual ability to perform daily tasks on a PC, as previous studies have relied on participants self-assessing their abilities via questionnaires... "The study revealed that, in particular, working memory, attention, and executive functions stand out as the key abilities. When using a computer, you must determine the order in which things are done and keep in mind what has already been done. A purely mathematical or logical ability does not help in the same way," says university lecturer Viljami Salmela [from the University of Helsinki]. "Our results suggest that contemporary user interfaces are getting so complex that their design is starting to affect inclusivity," their paper concludes, saying that it ultimately raises a question. "How can we design user interfaces to decrease the role of cognitive abilities."

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