A CRISPR-based drug given to study participants by infusion is raising hopes for a much easier way to lower cholesterol, reports CNN: With a snip of a gene, doctors may one day permanently lower dangerously high cholesterol, possibly removing the need for medication, according to a new pilot study published Saturday in the New England Journal of Medicine. The study was extremely small — only 15 patients with severe disease — and was meant to test the safety of a new medication delivered by CRISPR-Cas9, a biological sort of scissor which cuts a targeted gene to modify or turn it on or off. Preliminary results, however, showed nearly a 50% reduction in low-density lipoprotein, or LDL, the "bad" cholesterol which plays a major role in heart disease — the No.1 killer of adults in the United States and worldwide. The study, which will be presented Saturday at the American Heart Association Scientific Sessions in New Orleans, also found an average 55% reduction in triglycerides, a different type of fat in the blood that is also linked to an increased risk of cardiovascular disease. "We hope this is a permanent solution, where younger people with severe disease can undergo a 'one and done' gene therapy and have reduced LDL and triglycerides for the rest of their lives," said senior study author Dr. Steven Nissen, chief academic officer of the Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute at Cleveland Clinic in Ohio.... Today, cardiologists want people with existing heart disease or those born with a predisposition for hard-to-control cholesterol to lower their LDL well below 100, which is the average in the US, said Dr. Pradeep Natarajan, director of preventive cardiology at Massachusetts General Hospital and associate professor of medicine at Harvard Medical School in Boston... People with a nonfunctioning ANGPTL3 gene — which Natarajan says applies to about 1 in 250 people in the US — have lifelong levels of low LDL cholesterol and triglycerides without any apparent negative consequences. They also have exceedingly low or no risk for cardiovascular disease. "It's a naturally occurring mutation that's protective against cardiovascular disease," said Nissen, who holds the Lewis and Patricia Dickey Chair in Cardiovascular Medicine at Cleveland Clinic. "And now that CRISPR is here, we have the ability to change other people's genes so they too can have this protection." "Phase 2 clinical trials will begin soon, quickly followed by Phase 3 trials, which are designed to show the effect of the drug on a larger population, Nissen said." And CNN quotes Nissen as saying "We hope to do all this by the end of next year. We're moving very fast because this is a huge unmet medical need — millions of people have these disorders and many of them are not on treatment or have stopped treatment for whatever reason."

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A former Business Analyst reportedly filed a class action lawsuit claiming that for years, hundreds of remote employees at Bank of America first had to boot up complex computer systems before their paid work began, reports Human Resources Director magazine: Tava Martin, who worked both remotely and at the company's Jacksonville facility, says the financial institution required her and fellow hourly workers to log into multiple security systems, download spreadsheets, and connect to virtual private networks — all before the clock started ticking on their workday. The process wasn't quick. According to the filing in the United States District Court for the Western District of North Carolina, employees needed 15 to 30 minutes each morning just to get their systems running. When technical problems occurred, it took even longer... Workers turned on their computers, waited for Windows to load, grabbed their cell phones to request a security token for the company's VPN, waited for that token to arrive, logged into the network, opened required web applications with separate passwords, and downloaded the Excel files they needed for the day. Only then could they start taking calls from business customers about regulatory reporting requirements... The unpaid work didn't stop at startup. During unpaid lunch breaks, many systems would automatically disconnect or otherwise lose connection, forcing employees to repeat portions of the login process — approximately three to five minutes of uncompensated time on most days, sometimes longer when a complete reboot was required. After shifts ended, workers had to log out of all programs and shut down their computers securely, adding another two to three minutes. Thanks to Slashdot reader Joe_Dragon for sharing the article.

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The Associated Press reports that "For the past decade, Dr. Priscilla Chan and her husband Mark Zuckerberg have focused part of their philanthropy on a lofty goal — 'to cure, prevent or manage all disease' — if not in their lifetime, then in their children's." During that decade they also funded other initiatives (including underprivileged schools and immigration reform), according to the article. But there's a change coming: Now, the billionaire couple is shifting the bulk of their philanthropic resources to Biohub, the pair's science organization, and focusing on using artificial intelligence to accelerate scientific discovery. The idea is to develop virtual, AI-based cell models to understand how they work in the human body, study inflammation and use AI to "harness the immune system" for disease detection, prevention and treatment. "I feel like the science work that we've done, the Biohub model in particular, has been the most impactful thing that we have done. So we want to really double down on that. Biohub is going to be the main focus of our philanthropy going forward," Zuckerberg said Wednesday evening at an event at the Biohub Imaging Institute in Redwood City, California.... Chan and Zuckerberg have pledged 99% of their lifetime wealth — from shares of Meta Platforms, where Zuckerberg is CEO — toward these efforts... On Thursday, Chan and Zuckerberg also announced that Biohub has hired the team at EvolutionaryScale, an AI research lab that has created large-scale AI systems for the life sciences... Biohub's ambition for the next years and decades is to create virtual cell systems that would not have been possible without recent advances in AI. Similar to how large language models learn from vast databases of digital books, online writings and other media, its researchers and scientists are working toward building virtual systems that serve as digital representations of human physiology on all levels, such as molecular, cellular or genome. As it is open source — free and publicly available — scientists can then conduct virtual experiments on a scale not possible in physical laboratories. "We will continue the model we've pioneered of bringing together scientists and engineers in our own state-of-the-art labs to build tools that advance the field," according to Thursday's blog post. "We'll then use those tools to generate new data sets for training new biological AI models to create virtual cells and immune systems and engineer our cells to detect and treat disease.... "We have also established the first large-scale GPU cluster for biological research, as well as the largest datasets around human cell types. This collection of resources does not exist anywhere else."

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Long-time Slashdot reader AmiMoJo shared this report from Marine Insight: The world's largest cargo sailboat, Neoliner Origin, completed its first transatlantic voyage on 30 October despite damage to one of its sails during the journey. The 136-metre-long vessel had to rely partly on its auxiliary motor and its remaining sail after the aft sail was damaged in a storm shortly after departure... Neoline, the company behind the project, said the damage reduced the vessel's ability to perform fully on wind power... The Neoliner Origin is designed to reduce greenhouse gas emissions by 80 to 90 percent compared to conventional diesel-powered cargo ships. According to the United Nations Conference on Trade and Development (UNCTAD), global shipping produces about 3 percent of worldwide greenhouse gas emissions... The ship can carry up to 5,300 tonnes of cargo, including containers, vehicles, machinery, and specialised goods. It arrived in Baltimore carrying Renault vehicles, French liqueurs, machinery, and other products. The Neoliner Origin is scheduled to make monthly voyages between Europe and North America, maintaining a commercial cruising speed of around 11 knots.

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"Internal documents have revealed that Meta has projected it earns billions from ignoring scam ads that its platforms then targeted to users most likely to click on them," writes Ars Technica, citing a lengthy report from Reuters. Reuters reports that Meta "for at least three years failed to identify and stop an avalanche of ads that exposed Facebook, Instagram and WhatsApp's billions of users to fraudulent e-commerce and investment schemes, illegal online casinos, and the sale of banned medical products..." On average, one December 2024 document notes, the company shows its platforms' users an estimated 15 billion "higher risk" scam advertisements — those that show clear signs of being fraudulent — every day. Meta earns about $7 billion in annualized revenue from this category of scam ads each year, another late 2024 document states. Much of the fraud came from marketers acting suspiciously enough to be flagged by Meta's internal warning systems. But the company only bans advertisers if its automated systems predict the marketers are at least 95% certain to be committing fraud, the documents show. If the company is less certain — but still believes the advertiser is a likely scammer — Meta charges higher ad rates as a penalty, according to the documents. The idea is to dissuade suspect advertisers from placing ads. The documents further note that users who click on scam ads are likely to see more of them because of Meta's ad-personalization system, which tries to deliver ads based on a user's interests... The documents indicate that Meta's own research suggests its products have become a pillar of the global fraud economy. A May 2025 presentation by its safety staff estimated that the company's platforms were involved in a third of all successful scams in the U.S. Meta also acknowledged in other internal documents that some of its main competitors were doing a better job at weeding out fraud on their platforms... The documents note that Meta plans to try to cut the share of Facebook and Instagram revenue derived from scam ads. In the meantime, Meta has internally acknowledged that regulatory fines for scam ads are certain, and anticipates penalties of up to $1 billion, according to one internal document. But those fines would be much smaller than Meta's revenue from scam ads, a separate document from November 2024 states. Every six months, Meta earns $3.5 billion from just the portion of scam ads that "present higher legal risk," the document says, such as those falsely claiming to represent a consumer brand or public figure or demonstrating other signs of deceit. That figure almost certainly exceeds "the cost of any regulatory settlement involving scam ads...." A planning document for the first half of 2023 notes that everyone who worked on the team handling advertiser concerns about brand-rights issues had been laid off. The company was also devoting resources so heavily to virtual reality and AI that safety staffers were ordered to restrict their use of Meta's computing resources. They were instructed merely to "keep the lights on...." Meta also was ignoring the vast majority of user reports of scams, a document from 2023 indicates. By that year, safety staffers estimated that Facebook and Instagram users each week were filing about 100,000 valid reports of fraudsters messaging them, the document says. But Meta ignored or incorrectly rejected 96% of them. Meta's safety staff resolved to do better. In the future, the company hoped to dismiss no more than 75% of valid scam reports, according to another 2023 document. A small advertiser would have to get flagged for promoting financial fraud at least eight times before Meta blocked it, a 2024 document states. Some bigger spenders — known as "High Value Accounts" — could accrue more than 500 strikes without Meta shutting them down, other documents say. Thanks to long-time Slashdot reader schwit1 for sharing the article.

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Long-time Slashdot reader AmiMoJo shared this report from Linuxiac: The Japanese branch of Mozilla's Support Mozilla (SUMO) community — responsible for localizing and maintaining Japanese-language support documentation for Firefox and other Mozilla products (consisting of Japanese native speakers) — has officially disbanded after more than two decades of voluntary work... SUMO, short for Support Mozilla, is the umbrella project for Mozilla's user support platform, support.mozilla.org, that brings together volunteers and contributors worldwide who translate, maintain, and update documentation, tutorials, and troubleshooting guides for Firefox, Thunderbird, and other Mozilla products... According to marsf, the long-time locale leader of the Japanese SUMO team, the decision to disband was triggered by the recent introduction of an automated translation system known as Sumobot. Deployed on October 22, the bot began editing and approving Japanese Knowledge Base articles without community oversight. The article notes marsf's complaints in a post to the SUMO discussion forum, including the fact that the new automated system automatically approved machine-translated content with only a 72-hour window for human review. As a result, more than 300 Knowledge Base articles were overwritten on the production server, which marsf called "mass destruction of our work."

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American multinational freight company UPS "has grounded its fleet of MD-11 aircraft," reports the Guardian, "days after a cargo plane crash that killed at least 13 people in Kentucky. The grounded MD-11s are the same type of plane involved in Tuesday's crash in Louisville. They were originally built by McDonnell Douglas until it was taken over by Boeing." More details from NBC News: UPS said the move to temporarily ground its MD-11 fleet was made "out of an abundance of caution and in the interest of safety." MD-11s make up 9% of the company's air fleet, it said. "We made this decision proactively at the recommendation of the aircraft manufacturer. Nothing is more important to us than the safety of our employees and the communities we serve," UPS spokesman Jim Mayer said... FedEx said early Saturday that it was also grounding its MD-11s. The UPS rival has 28 such planes in operation, out of a fleet of around 700, FedEx said. Video shows that the left engine of the plane caught fire during takeoff and immediately detached, National Transportation Safety Board member Todd Inman said Wednesday. The National Transportation Safety Board is the lead agency in the investigation. Thanks to long-time Slashdot reader echo123 for suggesting the article.

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"Maybe you've heard that artificial intelligence is a bubble poised to burst," writes a Washington Post technology columnist. "Maybe you have heard that it isn't. (No one really knows either way, but that won't stop the bros from jabbering about it constantly.)" "But I can confidently tell you that the money being thrown around for AI is so huge that numbers have lost all meaning." The companies pouring money in are so rich and so power-hungry (in multiple meanings of that term) that our puny human brains cannot really comprehend. So let's try to give some meaning and context to the stratospheric numbers in AI. Is it a bubble? Eh, who knows. But it is completely bonkers. In just the past year, the four richest companies developing AI — Microsoft, Google, Amazon and Meta — have spent roughly $360 billion combined for big-ticket projects, which included building AI data centers and stuffing them with computer chips and equipment, according to my analysis of financial disclosures.... How do companies pay for the enormous sums they are lavishing on AI? Mostly, these companies make so much money that they can afford to go bananas... Eight of the world's top 10 most valuable companies are AI-centric or AI-ish American corporate giants — Nvidia, Apple, Microsoft, Google, Amazon, Broadcom, Meta and Tesla. That's according to tallies from S&P Global Market Intelligence based on the total price of the companies' stock held by investors. My analysis of the S&P data shows that the collective worth of those eight giants, $23 trillion, is more than the value of the next 96 most valuable U.S. companies put together, which includes many still very rich names such as JPMorgan, Walmart, Visa and ExxonMobil. No. 1 on that list, the AI computer chip seller Nvidia, last week become the first company in history to reach a stock market value of $5 trillion. That alone was more than the value of entire stock markets in most countries, Bloomberg News reported, other than the five biggest (in the U.S., China, Japan, Hong Kong and India)... All the announced or under-construction data centers for powering AI would consume roughly as much electricity as 44 million households in the United States if they run full tilt, according to a recent analysis by the Barclays investment bank as reported by the Financial Times. For context, that's nearly one-third of the total number of residential housing units in the entire country, according to U.S. Census Bureau housing estimates for 2024.

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"During the past two years or so I have been slow-rolling an effort to port the Linux kernel to WebAssembly," reads a surprising post on the Linux kernel mailing list. I'm now at the point where the kernel boots and I can run basic programs from a shell. As you will see if you play around with it for a bit, it's not very stable and will crash sooner or later, but I think this is a good first step. Wasm is not necessarily only targeting the web, but that's how I have been developing this project... This is Linux, booting in your browser tab, accelerated by Wasm. Phoronix warns that "there are stability issues and it didn't take me long either to trigger crashes for this Linux kernel WASM port when running within Google Chrome."

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"Rockstar Games fired dozens of employees," reports Bloomberg, "in a move that a British trade union said was designed to prevent the workers from unionizing. The company said they were fired for misconduct." TheGrand Theft Automaker terminatedbetween 30 and 40 staffersacross multipleoffices in the UK and Canada on Thursday, according to aspokesperson for the Independent Workers' Union of Great Britain (IWGB). All of the employees were part of a private trade union chat groupon Discord and were either members of the union or attempting to organize at the company, the union spokesperson said. "Rockstar has just carried out one of the most blatant and ruthless acts of union busting in the history of the games industry," Alex Marshall, president of theIWGB, said in a statement. "This flagrant contempt for the law and for the lives of the workers who bring in their billions is an insult to their fans and the global industry." On BlueSky the IWGB union posted "We won't back down, and we're not scared — we will fight for every member to be reinstated." Bloomberg notes that Grand Theft Auto VIis slated for release on May 26, 2026, "and is expected to be one of the top-selling video games of all time."

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"It finally happened," writes the GamingOnLinux site: Linux gamers on Steam as of the Steam Hardware & Software Survey for October 2025 have crossed over the elusive 3% mark. The trend has been clear for sometime, and with Windows 10 ending support, it was quite likely this was going to be the time for it to happen as more people try out Linux... Overall, 3% might not seem like much to some, but again — that trend is very clear and equates to millions of people. The last time Valve officially gave a proper monthly active user count was in 2022, and we know Steam has grown a lot since then, but even going by that original number would put monthly active Linux users at well over 4 million. Additional details from Phoronix: The only time Steam on Linux use was close to the 3% mark was when Steam on Linux initially debuted a decade ago and at that time the overall Steam user-base was much smaller than it is today. Long story short, thanks to the ongoing success of Valve's Steam Deck and other handhelds plus Steam Play (Proton) working out so well, these October numbers are the best yet... a hearty 0.41% increase to Linux... landing its overall marketshare at 3.05%. Windows meanwhile was at 94.84% (falling below 95% for the first time in a while) and macOS at 2.11%. For comparison, in October 2024 Steam on Linux was at 2.00%. The Linux-specific data shows SteamOS commanding around 27% of all the Linux installs at large. SteamOS most notably being on the Steam Deck hardware.

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TechCrunch reports: OpenAI CEO Sam Altman recently said that the company is doing "well more" than $13 billion in annual revenue — and he sounded a little testy when pressed on how it will pay for its massive spending commitments. His comments came up during a joint interviewon the Bg2 podcast between Altman and Microsoft CEO Satya Nadella about the partnership between their companies. Host Brad Gerstner (who's also founder and CEO of Altimeter Capital) brought upreports that OpenAI is currently bringing in around $13 billion in revenue — a sizable amount, but one that's dwarfed by more than $1 trillion in spending commitments for computing infrastructure that OpenAI has made for the next decade. "First of all, we're doing well more revenue than that. Second of all, Brad, if you want to sell your shares, I'll find you a buyer," Altman said, prompting laughs from Nadella. "I just — enough. I think there are a lot of people who would love to buy OpenAI shares." Altman's answer continued, making the case for OpenAI's business model. "We do plan for revenue to grow steeply. Revenue is growing steeply. We are taking a forward bet that it's going to continue to grow and that not only will ChatGPT keep growing, but we will be able to become one of the important AI clouds, that our consumer device business will be a significant and important thing. That AI that can automate science will create huge value... "We carefully plan, we understand where the technology — where the capability — is going to go, and the products we can build around that and the revenue we can generate. We might screw it up — like, this is the bet that we're making, and we're taking a risk along with that." (That bet-with-risks seems to be the $1.4 trillion in spending commitments — but Altman suggests it's offset by another absolutely certain risk: "If we don't have the compute, we will not be able to generate the revenue or make the models at this kind of scale.") Satya Nadella, Microsoft's CEO, added his own defense, "as both a partner and an investor. There has not been a single business plan that I've seen from OpenAI that they have put in and not beaten it. So in some sense, this is the one place where in terms of their growth — and just even the business — it's been unbelievable execution, quite frankly..."

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"An engineer got curious about how his iLife A11 smart vacuum worked and monitored the network traffic coming from the device," writes Tom's Hardware. "That's when he noticed it was constantly sending logs and telemetry data to the manufacturer — something he hadn't consented to." The user, Harishankar, decided to block the telemetry servers' IP addresses on his network, while keeping the firmware and OTA servers open. While his smart gadget worked for a while, it just refused to turn on soon after... He sent it to the service center multiple times, wherein the technicians would turn it on and see nothing wrong with the vacuum. When they returned it to him, it would work for a few days and then fail to boot again... [H]e decided to disassemble the thing to determine what killed it and to see if he could get it working again... [He discovered] a GD32F103 microcontroller to manage its plethora of sensors, including Lidar, gyroscopes, and encoders. He created PCB connectors and wrote Python scripts to control them with a computer, presumably to test each piece individually and identify what went wrong. From there, he built a Raspberry Pi joystick to manually drive the vacuum, proving that there was nothing wrong with the hardware. From this, he looked at its software and operating system, and that's where he discovered the dark truth: his smart vacuum was a security nightmare and a black hole for his personal data. First of all, it's Android Debug Bridge, which gives him full root access to the vacuum, wasn't protected by any kind of password or encryption. The manufacturer added a makeshift security protocol by omitting a crucial file, which caused it to disconnect soon after booting, but Harishankar easily bypassed it. He then discovered that it used Google Cartographer to build a live 3D map of his home. This isn't unusual, by far. After all, it's a smart vacuum, and it needs that data to navigate around his home. However, the concerning thing is that it was sending off all this data to the manufacturer's server. It makes sense for the device to send this data to the manufacturer, as its onboard SoC is nowhere near powerful enough to process all that data. However, it seems that iLife did not clear this with its customers. Furthermore, the engineer made one disturbing discovery — deep in the logs of his non-functioning smart vacuum, he found a command with a timestamp that matched exactly the time the gadget stopped working. This was clearly a kill command, and after he reversed it and rebooted the appliance, it roared back to life. Thanks to long-time Slashdot reader registrations_suck for sharing the article.

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"Ubuntu's decision to switch to Rust-based coreutils in 25.10 hasn't been the smoothest ride," writes the blog OMG Ubuntu, "as the latest — albeit now resolved — bug underscores." [Coreutils] are used by a number of processes, apps and scripts, including Ubuntu's own unattended-upgrades process, which automatically checks for new software updates. Alas, the Rust-based version of date had a bug which meant Ubuntu 25.10 desktops, servers, cloud and container images were not able to automatically check for updates when configured. Unattended-upgrades hooks into the date utility to check the timestamp of a reference file of when an update check was last run and, past a certain date, checks again. But date was incorrectly showing the current date, always. A fix has been issued so only Ubuntu 25.10 installs withrust-coreutils 0.2.2-0ubuntu2 (or earlier) are affected.

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"AI isn't just a tool anymore; it's an integral part of the development experience," argues GitHub's blog. So "Agents shouldn't be bolted on. They should work the way you already work..." So this week GitHub announced "Agent HQ," which CNBC describes as a "mission control" interface "that will allow software developers to manage coding agents from multiple vendors on a single platform." Developers have a range of new capabilities at their fingertips because of these agents, but it can require a lot of effort to keep track of them all individually, said GitHub COO Kyle Daigle. Developers will now be able to manage agents from GitHub, OpenAI, Google, Anthropic, xAI and Cognition in one place with Agent HQ. "We want to bring a little bit of order to the chaos of innovation," Daigle told CNBC in an interview. "With so many different agents, there's so many different ways of kicking off these asynchronous tasks, and so our big opportunity here is to bring this all together." Agent HQ users will be able to access a command center where they can assign, steer and monitor the work of multiple agents... The third-party agents will begin rolling out to GitHub Copilot subscribers in the coming months, but Copilot Pro+ users will be able to access OpenAI Codex in VS Code Insiders this week, the company said. "We're into this wave two era," GitHub's COO Mario Rodriguez told VentureBeat, an era that's "going to be multimodal, it's going to be agentic and it's going to have these new experiences that will feel AI native...." Or, as VentureBeat sees it, GitHub "is positioning itself as the essential orchestration layer beneath them all..." Just as the company transformed Git, pull requests and CI/CD into collaborative workflows, it's now trying to do the same with a fragmented AI coding landscape... The technical architecture addresses a critical enterprise concern: Security. Unlike standalone agent implementations where users must grant broad repository access, GitHub's Agent HQ implements granular controls at the platform level... Agents operating through Agent HQ can only commit to designated branches. They run within sandboxed GitHub Actions environments with firewall protections. They operate under strict identity controls. [GitHub COO] Rodriguez explained that even if an agent goes rogue, the firewall prevents it from accessing external networks or exfiltrating data unless those protections are explicitly disabled. Beyond managing third-party agents, GitHub is introducing two technical capabilities that set Agent HQ apart from alternative approaches like Cursor's standalone editor or Anthropic's Claude integration. Custom agents via AGENTS.md files: Enterprises can now create source-controlled configuration files that define specific rules, tools and guardrails for how Copilot behaves. For example, a company could specify "prefer this logger" or "use table-driven tests for all handlers." This permanently encodes organizational standards without requiring developers to re-prompt every time... Native Model Context Protocol (MCP) support: VS Code now includes a GitHub MCP Registry. Developers can discover, install and enable MCP servers with a single click. They can then create custom agents that combine these tools with specific system prompts. This positions GitHub as the integration point between the emerging MCP ecosystem and actual developer workflows. MCP, introduced by Anthropic but rapidly gaining industry support, is becoming a de facto standard for agent-to-tool communication. By supporting the full specification, GitHub can orchestrate agents that need access to external services without each agent implementing its own integration logic. GitHub is also shipping new capabilities within VS Code itself. Plan Mode allows developers to collaborate with Copilot on building step-by-step project approaches. The AI asks clarifying questions before any code is written. Once approved, the plan can be executed either locally in VS Code or by cloud-based agents. The feature addresses a common failure mode in AI coding: Beginning implementation before requirements are fully understood. By forcing an explicit planning phase, GitHub aims to reduce wasted effort and improve output quality. More significantly, GitHub's code review feature is becoming agentic. The new implementation will use GitHub's CodeQL engine, which previously largely focused on security vulnerabilities to identify bugs and maintainability issues. The code review agent will automatically scan agent-generated pull requests before human review. This creates a two-stage quality gate. "Don't let this little bit of news float past you like all those self-satisfied marketing pitches we semi-hear and ignore," writes ZDNet: If it works and remains reliable, this is actually a very big deal... Tech companies, especially the giant ones, often like to talk "open" but then do their level best to engineer lock-in to their solution and their solution alone. Sure, most of them offer some sort of export tool, but the barrier to moving from one tool to another is often huge... [T]he idea that you can continue to use your favorite agent or agents in GitHub, fully integrated into the GitHub tool path, is powerful. It means there's a chance developers might not have to suffer the walled garden effect that so many companies have strived for to lock in their customers.

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OpenAI "hasn't yet turned a profit," notes Wall Street Journal business columnist Tim Higgins. "Its annual revenue is 2% of Amazon.com's sales. "Its future is uncertain beyond the hope of ushering in a godlike artificial intelligence that might help cure cancer and transform work and life as we know it. Still, it is brimming with hope and excitement. "But what if OpenAI fails?" There's real concern that through many complicated and murky tech deals aimed at bolstering OpenAI's finances, the startup has become too big to fail. Or, put another way, if the hype and hope around Chief Executive Sam Altman's vision of the AI future fails to materialize, it could create systemic risk to the part of the U.S. economy likely keeping us out of recession. That's rarefied air, especially for a startup. Few worried about what would happen if Pets.com failed in the dot-com boom. We saw in 2008-09 with the bank rescues and the Chrysler and General Motors bailouts what happens in the U.S. when certain companies become too big to fail... [A]fter a lengthy effort to reorganize itself, OpenAI announced moves that will allow it to have a simpler corporate structure. This will help it to raise money from private investors and, presumably, become a publicly traded company one day. Already, some are talking about how OpenAI might be the first trillion-dollar initial public offering... Nobody is saying OpenAI is dabbling in anything like liar loans or subprime mortgages. But the startup is engaging in complex deals with the key tech-industry pillars, the sorts of companies making the guts of the AI computing revolution, such as chips and Ethernet cables. Those companies, including Nvidia and Oracle, are partnering with OpenAI, which in turn is committing to make big purchases in coming years as part of its growth ambitions. Supporters would argue it is just savvy dealmaking. A company like Nvidia, for example, is putting money into a market-making startup while OpenAI is using the lofty value of its private equity to acquire physical assets... They're rooting for OpenAI as a once-in-a-generational chance to unseat the winners of the last tech cycles. After all, for some, OpenAI is the next Apple, Facebook, Google and Tesla wrapped up in one. It is akin to a company with limitless potential to disrupt the smartphone market, create its own social-media network, replace the search engine, usher in a robot future and reshape nearly every business and industry.... To others, however, OpenAI is something akin to tulip mania, the harbinger of the Great Depression, or the next dot-com bubble. Or worse, they see, a jobs killer and mad scientist intent on making Frankenstein. But that's counting on OpenAI's success.

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Slashdot reader BrianFagioli summarizes some news from Nerds.xyz: Creative Technology has launched Sound Blaster Re:Imagine, a modular, Linux-powered audio hub that reimagines the classic PC sound card for the modern age. The device acts as both a high-end digital-to-analog converter (DAC) and a customizable control deck that connects PCs, consoles, phones, and tablets in one setup. Users can instantly switch inputs and outputs, while developers get full hardware access through an SDK for creating their own apps. It even supports AI-driven features like an on-device DJ, a revived "Dr. Sbaitso" speech synthesizer, and a built-in DOS emulator for retro gaming. The Kickstarter campaign has already raised more than $150,000, far surpassing its initial goal of $15,000 with over 50 days remaining. Each unit ships with a modular "Horizon" base and swappable knobs, sliders, and buttons, while a larger "Vertex" version will unlock at a higher funding milestone. Running an unspecified Linux build, Re:Imagine positions itself as both a nostalgic nod to Sound Blaster's roots and a new open platform for creators, gamers, and tinkerers.

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San Francisco's local newscast ABC7 runs a consumer advocacy segment called "7 on Your Side". They received a disturbing call for help from Dave Dornlas, treasurer of a nonprofit supporting a local library: GoFundMe has taken upon itself to create "nonprofit pages" for 1.4 million 501C-3 organizations using public IRS data along with information from trusted partners like the PayPal Giving Fund. "The fact that they would just on their own build pages for nonprofits that they've never spoken to is a problem," [Dornlas] said. "I'm a believer in opt-in, not opt-out...." Dornlas says he struggled to find anyone to contact from GoFundMe about this... Dave's other frustration is tied to the company's optional tipping feature on the platform. "GoFundMe also solicits a tip of 14.5%. In other words, 'We're doing this and we're great people. Give us 14.5% to do this' — which doesn't have to happen," Dornlas said. "That's what bothers me." When 7 On Your Side checked, the optional tip was actually set for 16.5%. The consumer is required to move the bar to adjust accordingly... The tip would be in addition to the 2.2% transaction fee GoFundMe charges nonprofits, plus $0.30 per donation. That fee goes up to 2.9% for individual fundraisers. Now both GoFundMe pages of Dornlas's nonprofits have been removed from the site. Any organization can do so, by clicking "unpublish" on the platform. But GoFundMe's move drew strong criticism from the Center for Nonprofit Excellence (a Kentucky-based membership organization with over 500 members). GoFundMe's move, they say, creates "confusion for donors and supporters who are unsure of the legitimacy of the fundraising pages. In some cases, GoFundMe included incorrect information, outdated logos, and other inaccuracies that compromise and misrepresent nonprofits' brand, mission, strategy, and message." And GoFundMe's processing fees and tips "ultimately result in fewer resources for nonprofits than if donors contributed directly through the organization." But there's more... GoFundMe has initiated SEO optimization as the default for the donation pages to improve their visibility when individuals search forinformation about nonprofits online. This could result in GoFundMe'spages ranking higher than the nonprofit's own website, pulling away potential donors and supporters... Without adequate safeguards in place, nonprofits report serious issues, ranging from unauthorized individuals claiming donations and the inability to remove pages without first agreeing to GoFundMe's terms and conditions or sharing sensitive banking information. The Center for Nonprofit Excellence has now joined with the National Council of Nonprofits — America's largest network of nonprofits, with over 25,000 members — to officially urge GoFundMe to immediately rectify the situation. Thanks to long-time Slashdot reader Arrogant-Bastard for sharing the article.

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"Amazon has deployed Rivian's electric delivery vans in Canada for the first time," reports CleanTechnica, with 50 now deployed in the Vancouver area. Amazon's director of Global Fleet and Products says there's now over 35,000 electric vans deployed globally — and that they've delivered more than 1.5 billion packages. More from the blog Teslarati: In December 2024, the companies announced they had successfully deployed 20,000 EDVs across the U.S. In the first half of this year, 10,000 additional vans were delivered, and Amazon's fleet had grown to 30,000 EDVs by mid-2025. Amazon's fleet of EDVs continues to grow rapidly and has expanded to over 100 cities in the United States... The EDV is a model that is exclusive to Amazon, but Rivian sells the RCV, or Rivian Commercial Van, openly. It detailed some of the pricing and trim options back in January when it confirmed it had secured orders from various companies, including AT&T.

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"People are creating 'dumb homes,'" the VP of research at the Global Wellness Institute, tells the web site Axios. Some are swapping NASA-style setups for old-fashioned buttons, switches and knobs. Others are designing digital detox corners — all part of a bigger "analog wellness" movement... The return to analog hobbies and spacesis about more than nostalgia for pre-internet times, researchers say. A home where "technology is always in the background, working and listening, feels anxiety-producing" instead of restorative, architect Yan M. Wang tells Axios... Design media brand Dwell named the decline of smart homes a top trend for 2025 and beyond. Wealthy Los Angeles house hunters have started shunning WiFi-enabled, voice-activated appliances "to escape the $100 billion home-automation industry," according to the Hollywood Reporter. Meanwhile, landlines have found new fans — many of them parents who want to keep their kids off screens, the Washington Post reports.

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