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Aujourd’hui — 12 juin 2024Slashdot

The Rise and Fall of BNN Breaking, an AI-Generated News Outlet

Par : BeauHD
12 juin 2024 à 03:30
An anonymous reader quotes a report from the New York Times: The news was featured on MSN.com: "Prominent Irish broadcaster faces trial over alleged sexual misconduct." At the top of the story was a photo of Dave Fanning. But Mr. Fanning, an Irish D.J. and talk-show host famed for his discovery of the rock band U2, was not the broadcaster in question. "You wouldn't believe the amount of people who got in touch," said Mr. Fanning, who called the error "outrageous." The falsehood, visible for hours on the default homepage for anyone in Ireland who used Microsoft Edge as a browser, was the result of an artificial intelligence snafu. A fly-by-night journalism outlet called BNN Breaking had used an A.I. chatbot to paraphrase an article from another news site, according to a BNN employee. BNN added Mr. Fanning to the mix by including a photo of a "prominent Irish broadcaster." The story was then promoted by MSN, a web portal owned by Microsoft. The story was deleted from the internet a day later, but the damage to Mr. Fanning's reputation was not so easily undone, he said in a defamation lawsuit filed in Ireland against Microsoft and BNN Breaking. His is just one of many complaints against BNN, a site based in Hong Kong that published numerous falsehoods during its short time online as a result of what appeared to be generative A.I. errors. Mr. Fanning's complaint against BNN is one of many. The site based published numerous falsehoods during its short time online.Credit...Paulo Nunes dos Santos for The New York Times BNN went dormant in April, while The New York Times was reporting this article. The company and its founder did not respond to multiple requests for comment. Microsoft had no comment on MSN's featuring the misleading story with Mr. Fanning's photo or his defamation case, but the company said it had terminated its licensing agreement with BNN. During the two years that BNN was active, it had the veneer of a legitimate news service, claiming a worldwide roster of "seasoned" journalists and 10 million monthly visitors, surpassing the The Chicago Tribune's self-reported audience. Prominent news organizations like The Washington Post, Politico and The Guardian linked to BNN's stories. Google News often surfaced them, too. A closer look, however, would have revealed that individual journalists at BNN published lengthy stories as often as multiple times a minute, writing in generic prose familiar to anyone who has tinkered with the A.I. chatbot ChatGPT. BNN's "About Us" page featured an image of four children looking at a computer, some bearing the gnarled fingers that are a telltale sign of an A.I.-generated image. "How easily the site and its mistakes entered the ecosystem for legitimate news highlights a growing concern: A.I.-generated content is upending, and often poisoning, the online information supply," adds The Times. "NewsGuard, a company that monitors online misinformation, identified more than 800 websites that use A.I. to produce unreliable news content. The websites, which seem to operate with little to no human supervision, often have generic names -- such as iBusiness Day and Ireland Top News -- that are modeled after actual news outlets. They crank out material in more than a dozen languages, much of which is not clearly disclosed as being artificially generated, but could easily be mistaken as being created by human writers."

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Best Buy Is Laying Off More Employees As It Reckons With Falling Sales

Par : BeauHD
12 juin 2024 à 00:45
According to The Verge, Best Buy conducted another round of layoffs and job restructurings to "right size" the business in response to declining sales post-pandemic. Further layoffs and changes are expected throughout the year. From the report: The layoffs appeared to have mostly targeted in-home sales roles called designers, who would go to customers' homes to help identify products that would work in their space. It's not clear how many were let go, but designers who weren't laid off have been moved into a different, largely in-store role. Also, pay scales for a similar, existing in-store "consultant" position were revamped. Best Buy confirmed the layoffs in an email to The Verge but declined to share how many people were let go or how pay was changing. "Many of our team members were moved to new areas or roles where our customers need it most," Best Buy spokesperson Ryan Furlong told The Verge. He said some employees in Best Buy's "Design and Consult workforce" -- the collection of roles with in-store workers (called consultants) and in-home field sales positions (called designers) -- will be transitioned into a new "Premium Designer role." Best Buy has been drastically restructuring in recent months, responding to factors like falling sales after the pandemic spiked consumer electronics spending. Best Buy CEO Corie Barry told investors in February that they should expect layoffs this year, and two months ago, mass layoffs of Geek Squad employees were reported. Barry repeated similar things during the company's first quarter earnings call in May, saying that many of Best Buy's moves to "right size" its business "are being implemented throughout this year."

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Brazil Hires OpenAI To Cut Costs of Court Battles

Par : BeauHD
12 juin 2024 à 00:02
Brazil's government is partnering with OpenAI to use AI for expediting the screening and analysis of thousands of lawsuits to reduce costly court losses impacting the federal budget. Reuters reports: The AI service will flag to government the need to act on lawsuits before final decisions, mapping trends and potential action areas for the solicitor general's office (AGU). AGU told Reuters that Microsoft would provide the artificial intelligence services from ChatGPT creator OpenAI through its Azure cloud-computing platform. It did not say how much Brazil will pay for the services. AGU said the AI project would not replace the work of its members and employees. "It will help them gain efficiency and accuracy, with all activities fully supervised by humans," it said. Court-ordered debt payments have consumed a growing share of Brazil's federal budget. The government estimated it would spend 70.7 billion reais ($13.2 billion) next year on judicial decisions where it can no longer appeal. The figure does not include small-value claims, which historically amount to around 30 billion reais annually. The combined amount of over 100 billion reais represents a sharp increase from 37.3 billion reais in 2015. It is equivalent to about 1% of gross domestic product, or 15% more than the government expects to spend on unemployment insurance and wage bonuses to low-income workers next year. AGU did not provide a reason for Brazil's rising court costs.

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New York Launches Mobile Driver's Licenses

Par : BeauHD
11 juin 2024 à 23:20
New York has launched its mobile ID program, "giving residents the option to digitize their driver's license or non-driver ID," reports The Verge. From the report: Beginning today, the New York Mobile ID app is available from Apple's App Store and Google Play. The app can be used for identity verification at airports. A physical license, permit, or non-driver ID is required to activate a mobile ID; you'll need to take a photo of the front and back with your phone during the enrollment process. The news was announced during a media briefing at LaGuardia Airport on Tuesday that included New York's and Transportation Security Administration federal security director Robert Duffy, among other speakers. Their pitch is that mobile IDs "will revolutionize the way New Yorkers protect their identities and will significantly enhance the way they get through security at airports across the nation." State officials are also emphasizing that it's a voluntary option meant for convenience. "When you offer your mobile ID to TSA or anyone else who accepts it, you are in full control of sharing that information. They can only see the information they request to see," Schroeder said. "If you only need to prove your age, you can withhold other information that a verifier doesn't need to see." The app is designed so that your phone remains in your possession at all times -- you should never freely hand a device over to law enforcement -- and shows a QR code that can be scanned to verify your identity. Any changes to your license status such as renewals or suspensions are automatically pushed to the mobile version, and the digital ID also mirrors data like whether you're an organ donor. For now, acceptance of mobile IDs by businesses (and the police) is completely voluntary -- and there's no deadline in place for compliance -- so it's definitely too soon to start leaving your physical one at home. But bars and other small businesses can start accepting them immediately if they install the state's verifier app. The New York Mobile ID app can be used "at nearly 30 participating airports across the country including all terminals at LaGuardia and John F. Kennedy airports," according to a press release from Governor Kathy Hochul. New York joins a small list of states that have rolled out mobile driver's licenses, including Arizona, Colorado, Delaware, Georgia, Florida, Iowa, Louisiana, Maryland, Mississippi, Missouri, and Utah.

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Silicon Valley Salaries Are Shrinking, Leaving Workers In the Lurch

Par : BeauHD
11 juin 2024 à 22:40
An anonymous reader quotes a report from the Mercury News: Krista DeWeese has been laid off four times in the last eight years. She wakes up every morning feeling anxious. Will I lose my job today -- again? Will I have enough to pay the rent? Even though she's an educated, experienced marketing professional, worrisome thoughts trail the 47-year-old Fremont native's every waking moment. Currently a contract worker at a health science company, she has been struggling to find secure work that pays enough to keep up with the exorbitant cost of living in the Bay Area. She has a lot of company. The past year has been tough for the Bay Area, as thousands of layoffs skittered across the region. Even workers at Silicon Valley's tech titans -- including Meta, Apple and Google -- have faced job cuts. Since 2022, tech companies in the region have slashed roughly 40,000 jobs. And with each layoff, workers are entering a market that is less friendly to job seekers than it used to be. New research from tech advocacy organization Women Impact Tech, which examined job and salary data nationwide from 2020 to 2023, affirmed what many people already know: companies are tightening their belts -- slicing jobs and salaries alike -- and many people are struggling to find work that pays enough to live comfortably in the Bay Area. Despite having the highest tech salaries in the country, Silicon Valley has experienced the biggest drop in pay compared to other tech hubs, falling 15% from 2022 to 2023, according to Women Impact Tech. And with inflation, DeWeese and others are watching their spending power shrink. More than 10 years ago, she was earning over $100,000 in total compensation. That amount has dropped 15% since she was laid off from Yahoo in 2016, and has not increased since. "I feel like my career has been frozen in time," DeWeese said. "Things have been at a standstill." Paula Bratcher Ratliff, president of New York-based Women Impact Tech, said that the shrinking pay hits especially hard for women, given the continuing gender pay gap. "The Bay Area took one of the largest hits," Ratliff said. "Women make up about 28% of the entire workforce in tech. When you're seeing an overall decline at 15%, and for pay equity, women have not made much traction." [...] Despite the trend of shrinking salaries in the world's tech capital, Ratliff, with Women Impact Tech, doesn't believe it's necessarily a race to the bottom. "Today, about every company is a tech company, whether they're in retail, consumer goods or hospitality," Ratliff said. "There's so many opportunities in tech without having to focus on those jobs with the tech organizations alone. We're seeing great companies emerge." While it's still unclear where the light is at the end of the tunnel for DeWeese, she remains hopeful her situation will improve. "You have to have hope or else you're just going to live in fear of being let go, again and again," she said.

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Hier — 11 juin 2024Slashdot

Craig Federighi Says Apple Hopes TO Add Google Gemini, Other AI Models To iOS 18

Par : BeauHD
11 juin 2024 à 22:00
Yesterday, Apple made waves in the media when it revealed a partnership with OpenAI during its annual WWDC keynote. That announcement centered on Apple's decision to bring ChatGPT natively to iOS 18, including Siri and other first-party apps. During a followup interview on Monday, Apple executives Craig Federighi and John Giannandrea hinted at a possible agreement with Google Gemini and other AI chatbots in the future. 9to5Mac reports: Moderated by iJustine, the interview was held in Steve Jobs Theater this afternoon, featuring a discussion with John Giannandrea, Apple's Senior Vice President of Machine Learning and AI Strategy, and Craig Federighi, Senior Vice President of Software Engineering. During the interview, Federighi specifically referenced Apple's hopes to eventually let users choose between different models to use with Apple Intelligence. While ChatGPT from OpenAI is the only option right now, Federighi suggested that Google Gemini could come as an option down the line: "We think ultimately people are going to have a preference perhaps for certain models that they want to use, maybe one that's great for creative writing or one that they prefer for coding. And so we want to enable users ultimately to bring a model of their choice. And so we may look forward to doing integrations with different models like Google Gemini in the future. I mean, nothing to announce right now, but that's our direction." The decision to focus on ChatGPT at the start was because Apple wanted to "start with the best," according to Federighi.

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British Duo Arrested For SMS Phishing Via Homemade Cell Tower

Par : BeauHD
11 juin 2024 à 21:20
British police have arrested two individuals involved in an SMS-based phishing campaign using a unique device police described as a "homemade mobile antenna," "an illegitimate telephone mast," and a "text message blaster." This first-of-its-kind device in the UK was designed to send fraudulent texts impersonating banks and other official organizations, "all while allegedly bypassing network operators' anti-SMS-based phishing, or smishing, defenses," reports The Register. From the report: Thousands of messages were sent using this setup, City of London Police claimed on Friday, with those suspected to be behind the operation misrepresenting themselves as banks "and other official organizations" in their texts. [...] Huayong Xu, 32, of Alton Road in Croydon, was arrested on May 23 and remains the only individual identified by police in this investigation at this stage. He has been charged with possession of articles for use in fraud and will appear at Inner London Crown Court on June 26. The other individual, who wasn't identified and did not have their charges disclosed by police, was arrested on May 9 in Manchester and was bailed. [...] Without any additional information to go on, it's difficult to make any kind of assumption about what these "text message blaster" devices might be. However, one possibility, judging from the messaging from the police, is that the plod are referring to an IMSI catcher aka a Stingray, which acts as a cellphone tower to communicate with people's handhelds. But those are intended primarily for surveillance. What's more likely is that the suspected UK device is perhaps some kind of SIM bank or collection of phones programmed to spam out shedloads of SMSes at a time.

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Finnish Startup 'Flow' Claims It Can 100x Any CPU's Power With Its Companion Chip

Par : BeauHD
11 juin 2024 à 20:42
An anonymous reader quotes a report from TechCrunch: A Finnish startup called Flow Computing is making one of the wildest claims ever heard in silicon engineering: by adding its proprietary companion chip, any CPU can instantly double its performance, increasing to as much as 100x with software tweaks. If it works, it could help the industry keep up with the insatiable compute demand of AI makers. Flow is a spinout of VTT, a Finland state-backed research organization that's a bit like a national lab. The chip technology it's commercializing, which it has branded the Parallel Processing Unit, is the result of research performed at that lab (though VTT is an investor, the IP is owned by Flow). The claim, Flow is first to admit, is laughable on its face. You can't just magically squeeze extra performance out of CPUs across architectures and code bases. If so, Intel or AMD or whoever would have done it years ago. But Flow has been working on something that has been theoretically possible -- it's just that no one has been able to pull it off. Central Processing Units have come a long way since the early days of vacuum tubes and punch cards, but in some fundamental ways they're still the same. Their primary limitation is that as serial rather than parallel processors, they can only do one thing at a time. Of course, they switch that thing a billion times a second across multiple cores and pathways -- but these are all ways of accommodating the single-lane nature of the CPU. (A GPU, in contrast, does many related calculations at once but is specialized in certain operations.) "The CPU is the weakest link in computing," said Flow co-founder and CEO Timo Valtonen. "It's not up to its task, and this will need to change." CPUs have gotten very fast, but even with nanosecond-level responsiveness, there's a tremendous amount of waste in how instructions are carried out simply because of the basic limitation that one task needs to finish before the next one starts. (I'm simplifying here, not being a chip engineer myself.) What Flow claims to have done is remove this limitation, turning the CPU from a one-lane street into a multi-lane highway. The CPU is still limited to doing one task at a time, but Flow's Parallel Processing Unit (PPU), as they call it, essentially performs nanosecond-scale traffic management on-die to move tasks into and out of the processor faster than has previously been possible. [...] Flow is just now emerging from stealth, with [about $4.3 million] in pre-seed funding led by Butterfly Ventures, with participation from FOV Ventures, Sarsia, Stephen Industries, Superhero Capital and Business Finland. The primary challenge Flow faces is that for its technology to be integrated, it requires collaboration at the chip-design level. This means chipmakers need to redesign their products to include the PPU, which is a substantial investment. Given the industry's cautious nature and the existing roadmaps of major chip manufacturers, the uptake of this new technology might be slow. Companies are often reluctant to adopt unproven technologies that could disrupt their long-term plans. The white paper can be read here. A Flow Computing FAQ is also available here.

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Four More States Join US Monopoly Lawsuit Against Apple

Par : msmash
11 juin 2024 à 19:20
Four more U.S. states on Tuesday joined the Justice Department's lawsuit against Apple alleging the iPhone maker is monopolizing smartphone markets, the department said in a statement. From a report: The four states are Indiana, Massachusetts, Nevada and Washington, the Justice Department said. The original lawsuit was filed in March, and 15 states and the District of Columbia joined the lawsuit at the time. The lawsuit alleges that Apple uses its market power to get more money from consumers, developers, content creators, artists, publishers, small businesses and merchants. The civil lawsuit accuses Apple of an illegal monopoly on smartphones, maintained by imposing contractual restrictions on, and withholding critical access from, developers. The Justice Department has previously said Apple charges as much as $1,599 for an iPhone and makes a larger profit than any rival. Officials also said Apple imposes hidden charges on various business partners - from software developers to credit card companies and even rivals such as Alphabet's, Google, in ways that ultimately raise prices for consumers.

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The Mystery of an Alleged Data Broker's Data Breach

Par : msmash
11 juin 2024 à 18:40
An anonymous reader shares a report: Since April, a hacker with a history of selling stolen data has claimed a data breach of billions of records -- impacting at least 300 million people -- from a U.S. data broker, which would make it one of the largest alleged data breaches of the year. The data, seen by TechCrunch, on its own appears partly legitimate -- if imperfect. The stolen data, which was advertised on a known cybercrime forum, allegedly dates back years and includes U.S. citizens' full names, their home address history and Social Security numbers -- data that is widely available for sale by data brokers. But confirming the source of the alleged data theft has proven inconclusive; such is the nature of the data broker industry, which gobbles up individuals' personal data from disparate sources with little to no quality control. The alleged data broker in question, according to the hacker, is National Public Data, which bills itself as "one of the biggest providers of public records on the Internet." On its official website, National Public Data claimed to sell access to several databases: a "People Finder" one where customers can search by Social Security number, name and date of birth, address or telephone number; a database of U.S. consumer data "covering over 250 million individuals;" a database containing voter registration data that contains information on 100 million U.S. citizens; a criminal records one; and several more. Malware research group vx-underground said on X (formerly Twitter) that they reviewed the whole stolen database and could "confirm the data present in it is real and accurate."

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Bill Gates Moves Ahead With Nuclear Project Aimed At Revolutionizing Power Generation

Par : msmash
11 juin 2024 à 18:00
schwit1 shares a report: Bill Gates and his energy company are starting construction at their Wyoming site for a next-generation nuclear power plant he believes will "revolutionize" how power is generated. Gates was in the tiny community of Kemmerer Monday to break ground on the project. The co-founder of Microsoft is chairman of TerraPower. The company applied to the Nuclear Regulatory Commission in March for a construction permit for an advanced nuclear reactor that uses sodium, not water, for cooling. If approved, it would operate as a commercial nuclear power plant. The site is adjacent to PacifiCorp's Naughton Power Plant, which will stop burning coal in 2026 and natural gas a decade later, the utility said. Nuclear reactors operate without emitting planet-warming greenhouse gases. PacifiCorp plans to get carbon-free power from the reactor and says it is weighing how much nuclear to include in its long-range planning. The work begun Monday is aimed at having the site ready so TerraPower can build the reactor as quickly as possible if its permit is approved. Russia is at the forefront for developing sodium-cooled reactors.

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PC Makers Hopeful That Chromebook Refresh Cycles About To Kick In

Par : msmash
11 juin 2024 à 17:22
A Chromebook refresh looms despite Google trying to extend the life of laptops by offering a decade of service updates for models sold since 2021. From a report: Sales of the hardware, which flew off the shelves during the pandemic, ran out of steam in 2022 after buyers had their fill. The US education market generally accounts for 70 to 80 percent of annual orders. The sharp downturn left some vendors holding excess inventory. Yet the refresh cycle may be starting again, according to HP boss Enrique Lores. "So we have started to see a pickup of demand in education, and this, especially in the US, is a Chromebook opportunity," he told an audience of investors at Bernstein's 40th Annual Strategic Decision Conference. He forecast a flurry of activity in 2025 for "many million of units" from education but downplayed the impact on HP's balance sheet because the company pulled back from the product line after the pandemic. Lores said: "We are going after these deals because we think it's good, but it's not like ... a huge impact on the company."

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Solar-Powered Planes Take Flight

Par : msmash
11 juin 2024 à 16:40
The dream of perpetual, emissionless flight is getting closer to reality. Aviation giants, telecoms, investors, and military agencies are pouring millions into developing these prototypes, which could revolutionize aerial surveillance, emergency communications, and more. Solar planes absorb energy via panels covering their wings and bodies, allowing them to fly indefinitely as long as the sun shines. Advances in battery technology now enable longer flights and overnight operation, albeit with less power than jet fuel. These slow, lightweight aircraft can fly at altitudes and durations impossible for humans, making them ideal for monitoring, telecom, and disaster response. Companies like BAE Systems, Airbus, and Skydweller are racing to commercialize solar planes, with hopes of offering services by 2026-2027. The unregulated stratosphere is a key focus, with planes acting as "steerable satellites." WSJ adds: Most of the companies trying to commercialize solar planes are building aircraft that are lightweight, autonomous and can fly at altitudes and for lengths of time that humans can't tolerate. Unlike balloons, solar planes are steerable, a big advantage for monitoring a target on the ground or providing telecom coverage without being blown off course. They are also cheaper and closer to Earth than satellites, putting them in a sweet spot for services that can't currently be offered by either, executives in charge of solar-aircraft projects say. The planes can capture higher resolution photos or video than satellites, or deliver broadband internet from the air, another thing satellites can't do.

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Microsoft's New Outlook Security Changes Impact 3rd-Party Apps and Gmail Integration

Par : msmash
11 juin 2024 à 16:00
Microsoft is making changes to Outlook for consumers to enhance account security as part of its Secure Future Initiative. Starting September 16th, the company will end support for Basic Authentication for Outlook personal accounts, requiring users to access their email through apps using Modern Authentication. Microsoft will also remove the light version of the Outlook web application on August 19th and discontinue support for Gmail accounts in Outlook.com on June 30th. Users of affected email apps will be notified by the end of June to update their settings or reconfigure their accounts. The latest versions of Outlook, Apple Mail, and Thunderbird will support these changes, while the new Outlook for Windows and Mac apps will continue to support Gmail accounts. Microsoft is also migrating Windows Mail and Calendar users to the new Outlook for Windows app ahead of ending support for the built-in apps later this year.

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Mastercard To Phase Out Manual Card Entry For Online Payments In Europe By 2030

Par : msmash
11 juin 2024 à 15:20
storkus shares a report: Starting from 2030, Mastercard will no longer require Europeans to enter their card numbers manually when checking out online -- no matter what platform or device they're using. Mastercard will announce Tuesday in a fireside chat with CNBC that, by 2030, all cards it issues on its network in Europe will be tokenized. In other words, instead of the 16-digit card number we're all accustomed to using for transactions, this will be replaced with a randomly generated "token." The firm says it's been working with banks, fintechs, merchants and other partners to phase out manual card entry for e-commerce by 2030 in Europe, in favor of a one-click button across all online platforms. This will ensure that consumers' cards are secure against fraud attempts, Mastercard says. Users won't have to keep entering passwords every time they try to make a payment, as Mastercard is introducing passkeys that replace passwords. storkus comments: "This story, as currently written, says nothing about their plans outside Europe but in the past the USA in particular has been dead last in getting this kind of tech."

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African Elephants Address One Another With Individually Specific Name-Like Calls

Par : msmash
11 juin 2024 à 14:46
Abstract of a paper published on Nature: Personal names are a universal feature of human language, yet few analogues exist in other species. While dolphins and parrots address conspecifics by imitating the calls of the addressee, human names are not imitations of the sounds typically made by the named individual. Labelling objects or individuals without relying on imitation of the sounds made by the referent radically expands the expressive power of language. Thus, if non-imitative name analogues were found in other species, this could have important implications for our understanding of language evolution. Here we present evidence that wild African elephants address one another with individually specific calls, probably without relying on imitation of the receiver. We used machine learning to demonstrate that the receiver of a call could be predicted from the call's acoustic structure, regardless of how similar the call was to the receiver's vocalizations. Moreover, elephants differentially responded to playbacks of calls originally addressed to them relative to calls addressed to a different individual. Our findings offer evidence for individual addressing of conspecifics in elephants. They further suggest that, unlike other non-human animals, elephants probably do not rely on imitation of the receiver's calls to address one another.

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Raspberry Pi is Now a Public Company

Par : msmash
11 juin 2024 à 14:05
An anonymous reader shares a report: Who would have thought that Raspberry Pi, the maker of the tiny, cheap, single-board computers, would become a public company? Yet, this is exactly what's happening: Raspberry Pi priced its IPO on the London Stock Exchange on Tuesday morning at $3.56 per share, valuing it at $689 million. Shortly after that, the company's shares jumped a nice 32% to $4.70. It means that Raspberry Pi could end up raising more than $200 million during its IPO process. Raspberry Pi has sold 60 million units since its inception. In 2023 alone, Raspberry Pi generated $266 million in revenue and $66 million in gross profit. Raspberry Pi Ltd, the public company, is the commercial subsidiary of the Raspberry Pi Foundation. The Foundation says it wants to make it easier for people to learn coding through a low-cost, programmable computer. It also remains the main shareholder of Raspberry Pi Ltd.

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Advisory Panel of Experts Endorses FDA Approval of New Alzheimer's Drug

Par : BeauHD
11 juin 2024 à 13:00
An anonymous reader quotes a report from the New York Times: A committee of independent advisers to the Food and Drug Administration voted unanimously on Monday that the benefits outweigh the risks of the newest experimental drug for Alzheimer's disease. Alzheimer's afflicts more than six million Americans. It has no cure, and there is no treatment or lifestyle modification that can restore memory loss or reverse cognitive decline. The drug, made by Eli Lilly, is donanemab. It modestly slowed cognitive decline in patients in the early stages of the disease but also had significant safety risks, including swelling and bleeding in the brain. The committee concluded, though, that the consequences of Alzheimer's are so dire that even a modest benefit can be worthwhile. The F.D.A. usually follows the advice of the agency's advisory committees but not always. The drug is based on a long-held hypothesis that Alzheimer's disease begins when rough hard balls of amyloid, a protein, pile up in patients' brains, followed by a cascade of reactions leading to the death of neurons. The idea is to treat Alzheimer's by attacking amyloid, clearing it from the brain. Two similar amyloid-fighting drugs were approved recently: Leqembi, made by Eisai and Biogen, was approved last year. That drug's risks and modest benefits are similar to those of donanemab. Aduhelm, made by Biogen, is the other drug and was approved in 2021 but was discontinued because there was insufficient evidence that it could benefit patients. Donanemab was expected to be approved earlier this year, but in March, the F.D.A. decided that, instead, it would require donanemabto undergo the scrutiny of an independent advisory committee, a surprise to Eli Lilly. The vote, said Dr. Daniel Skovronsky, chief scientific officer at Lilly, confirmed his 25-year quest to find a way to intervene in the Alzheimer's disease. Now, he said, the company is starting a study that, it hopes, will stop the disease before symptoms even begin. At issue before the committee on Monday were some unusual aspects of donanemab's clinical trials, especially that study participants stopped taking the drug as soon as their amyloid was cleared. Some experts questioned whether stopping was the best strategy and whether clinical practice should include halting the treatment after amyloid clearance.

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Google Shuts Down GPay App, P2P Payments In the US

Par : BeauHD
11 juin 2024 à 10:00
After announcing a shut down date in February, Google's "GPay" app has officially stopped working for users in the U.S. "Starting on June 4, GPay -- as was the name of the app on Android homescreens -- automatically signed US users out," reports 9to5Google. "Attempting to login again explains how: 'The Google Pay US app is no longer available. You can still tap to pay using the Google Wallet app.'" From the report: Additionally, Google no longer offers peer-to-peer payments in the US. You can use the Google Pay website to view and transfer your balance -- money you've received or rewards -- to a bank account after June. The focus is now on Google Wallet and digitizing everything in your physical wallet. There's no equivalent finance tracking functionality. Meanwhile, "Google Pay" still exists as the name for what you're actually using when making a physical or online purchase with your phone.

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